Diabetes insípida central secundaria a meningitis neonatal por Escherichia coli / Central insipid diabetes secondary to neonatal meningitis due to EScherichia coli

Los criterios de diabetes insípida incluyen una osmolaridad en sagre elevada y unosniveles altos de sodio en sangre acompañados de una orina hipotónica. La respuesta a la administración intranasal de arginina-vasopresina es satisfactoria, normalizándose los niveles séricos de sodio e incrementándose la osmolaridad urinaria, seguidos de un mejor balance hídrico. El neonatólogo debe pensar en esta entidad en neonatos coninfección del sistema nervioso central. Estudios de imagen donde se observe una hemorragia en la región posterior del hipotálamo debe ser un signo de que ha ocurrido esta complicación. Este artículo describe el primer caso clínico de un neonato que desarrolló una diabetes insípida central secundaria a una meningitis por Escherichia coli

The criteria for diabetes insipidus reaching high levels of serum sodium and osmolarity, along with hypotonic urine. The response to intranasal arginine-vasopressin were prompt, normalizing the serum levels of sodium and increasing urinary osmolality, allowing a better metabolic balance. The neonatologist must be aware of the possibility of this kind of complication even in a normal child with central nervous system. Infection. Imaging studies showing hemorrhage in the region of the posterior hypothalamus must be a sign that this type of complication is able to occur. This report describes the first case of central diabetes insipidus secondary to Escherichia coli meningitis in a neonate

Probable metahemoglobinemia tras administración de EMLA® / Probable methemoglobinemia following EMLA® administration

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Adolescente con pérdida brusca de la conciencia y crisis comicial tras traumatismo craneoencefálico / Sudden loss of consciousness and comitial crisis after head injury in a teenager

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[Estimation of Neisseria meningitidis carriers among healthy subjects in contact with patients with meningococcal sepsis in the Madrid area]. / Tasa de portadores de Neisseriae meningitidis entre los contactos sanos de pacientes con sepsis meningocócica, en el área de Madrid.

We have studied 238 asymptomatic school children which had come in contact with one of 5 cases of meningococcal sepsis, which occurred between January 1992 to May 1992. The study was performed at the corresponding schools and oropharynx samples were immediately put into Thayer-Martin agar plates. The cases were identified as serotype C in three occasions and type B in two cases. The total carrier prevalence was 1.68%, all of which were serotype B. We did not find a significant relationship between asymptomatic carriers and meningococcal sepsis cases. In addition, all contacts were treated with rifampin. Control cultures were made after 15 days of the treatment and 100% of the carriers had negative cultures.

[Prevalence of Neisseria meningitidis carriers in a school population in the metropolitan area of Madrid]. / Prevalencia de portadores de Neisseriae meningitidis en una población escolar del área metropolitana de Madrid.

The prevalence of healthy carriers of Neisseriae meningitidis has been addressed by studying oropharynx samples of 1,172 schoolchildren in Madrid. The sample design took into consideration social status, age and sex. The total prevalence of healthy carriers was 2.30%, with 66% or these in the six year old age group (RR = 2.88, p < 0.005). Serotype B was found in 74% of the carriers, again mainly in the six year old age group, and 18.5% were serotype A, with most of them being found in the fourteen year age group. Serotype A carriers were females in 80% of the cases (p = 0.04). Serotype C was only found in six year old males. The prevalence of healthy carriers of Neisseriae meningitidis in our school-age population, in a non-epidemic situation, is in accord with results reported from other countries around us and agrees with previous reports of a higher prevalence among younger children and in males. In addition, the association between sex and some serotypes is confirmed.